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Learn more about the differences between RAVICTI and BUPHENYL and sign up to speak with a RAVICTI patient or caregiver.
What is RAVICTI?
RAVICTI (glycerol phenylbutyrate) Oral Liquid is a prescription medicine used for long-term management of high blood levels of ammonia (hyperammonemia) caused by a condition called a urea cycle disorder (UCD). RAVICTI should be used if the UCD cannot be managed with a low-protein diet and dietary supplements alone. RAVICTI must be used along with a low-protein diet and in some cases, dietary supplements.
RAVICTI is not used to treat extremely high levels of ammonia in the blood (hyperammonemic crisis) in people with UCDs.
It is not known if RAVICTI is safe and effective for the treatment of N-acetylglutamate synthase (NAGS) deficiency.
What is the most important safety information I should know about RAVICTI?
RAVICTI may cause serious side effects, including:
Nervous system side effects (Neurotoxicity). The breakdown of RAVICTI produces the byproduct phenylacetate (PAA), which may cause nervous system side effects.
Call your doctor or get medical help right away if you have any of these symptoms while taking RAVICTI:
Who should not take RAVICTI?
Do not take RAVICTI if you are allergic to phenylbutyrate. Call your doctor or go to the nearest hospital emergency room if you experience any of the following symptoms of an allergic reaction while taking RAVICTI:
What should I tell my doctor before taking RAVICTI?
Tell your doctor about any medical conditions and if you:
What are possible side effects of RAVICTI?
RAVICTI may cause serious side effects, including:
See "What is the most important information I should know about RAVICTI?"
The most common side effects of RAVICTI in adults include:
The most common side effects of RAVICTI in children 2 years to 17 years of age include:
The most common side effects of RAVICTI in children 2 months to less than 2 years of age include:
The most common side effects of RAVICTI in children less than 2 months of age include:
These are not all of the possible side effects of RAVICTI. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch or call 1-800-FDA-1088.
For additional important safety information, click here for the Medication Guide and discuss with your doctor.
What is BUPHENYL?
BUPHENYL (sodium phenylbutyrate) Tablets is a prescription medicine that can be taken by mouth and BUPHENYL (sodium phenylbutyrate) Powder is a prescription medicine that can be taken by mouth or feeding tube for the long-term management of high blood levels of ammonia (hyperammonemia) caused by a condition called a urea cycle disorder (UCD).
BUPHENYL only treats high blood levels of ammonia in patients with the following enzyme deficiencies:
BUPHENYL can be used in Infants up to 28 days old who have a complete enzyme deficiency, and in patients 1 month of age and older who have a partial enzyme deficiency and have a history of brain damage from high blood levels of ammonia.
BUPHENYL must be used along with a low-protein diet and in some cases, dietary supplements.
BUPHENYL is not used to treat acute (severe) hyperammonemia, which is a medical emergency.
IMPORTANT SAFETY INFORMATION
What is the most important safety information I should know about BUPHENYL?
BUPHENYL may cause serious side effects, including:
Nervous system side effects (Neurotoxicity). The breakdown of BUPHENYL produces the byproduct phenylacetate (PAA), which may cause nervous system side effects.
Who should not take BUPHENYL?
Do not take BUPHENYL if you are allergic to phenylbutyrate. Call your doctor or go to the nearest hospital emergency room if you experience an allergic reaction while taking BUPHENYL.
What should I tell my doctor before taking BUPHENYL?
Before taking BUPHENYL, tell your doctor about any medical conditions, including if you:
What are possible side effects of BUPHENYL?
BUPHENYL may cause serious side effects, including:
See "What is the most important safety information I should know about BUPHENYL?"
The most common side effects of BUPHENYL include:
These are not all of the possible side effects of BUPHENYL. Call your doctor for medical advice about side effects.
For additional important safety information, click here for the Full Prescribing Information and Patient Package Insert and discuss with your doctor.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
What is RAVICTI?
RAVICTI (glycerol phenylbutyrate) Oral Liquid is a prescription medicine used for long-term management of high blood levels of ammonia (hyperammonemia) caused by a condition called a urea cycle disorder (UCD). RAVICTI should be used if the UCD cannot be managed with a low-protein diet and dietary supplements alone. RAVICTI must be used along with a low-protein diet and in some cases, dietary supplements.
RAVICTI is not used to treat extremely high levels of ammonia in the blood (hyperammonemic crisis) in people with UCDs.
It is not known if RAVICTI is safe and effective for the treatment of N-acetylglutamate synthase (NAGS) deficiency.
What is the most important safety information I should know about RAVICTI?
RAVICTI may cause serious side effects, including:
Nervous system side effects (Neurotoxicity). The breakdown of RAVICTI produces the byproduct phenylacetate (PAA), which may cause nervous system side effects.
Call your doctor or get medical help right away if you have any of these symptoms while taking RAVICTI:
Who should not take RAVICTI?
Do not take RAVICTI if you are allergic to phenylbutyrate. Call your doctor or go to the nearest hospital emergency room if you experience any of the following symptoms of an allergic reaction while taking RAVICTI:
What should I tell my doctor before taking RAVICTI?
Tell your doctor about any medical conditions and if you:
What are possible side effects of RAVICTI?
RAVICTI may cause serious side effects, including:
See "What is the most important information I should know about RAVICTI?"
The most common side effects of RAVICTI in adults include:
The most common side effects of RAVICTI in children 2 years to 17 years of age include:
The most common side effects of RAVICTI in children 2 months to less than 2 years of age include:
The most common side effects of RAVICTI in children less than 2 months of age include:
These are not all of the possible side effects of RAVICTI. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch or call 1-800-FDA-1088.
For additional important safety information, click here for the Medication Guide and discuss with your doctor.
What is BUPHENYL?
BUPHENYL (sodium phenylbutyrate) Tablets is a prescription medicine that can be taken by mouth and BUPHENYL (sodium phenylbutyrate) Powder is a prescription medicine that can be taken by mouth or feeding tube for the long-term management of high blood levels of ammonia (hyperammonemia) caused by a condition called a urea cycle disorder (UCD).
BUPHENYL only treats high blood levels of ammonia in patients with the following enzyme deficiencies:
BUPHENYL can be used in Infants up to 28 days old who have a complete enzyme deficiency, and in patients 1 month of age and older who have a partial enzyme deficiency and have a history of brain damage from high blood levels of ammonia.
BUPHENYL must be used along with a low-protein diet and in some cases, dietary supplements.
BUPHENYL is not used to treat acute (severe) hyperammonemia, which is a medical emergency.
IMPORTANT SAFETY INFORMATION
What is the most important safety information I should know about BUPHENYL?
BUPHENYL may cause serious side effects, including:
Nervous system side effects (Neurotoxicity). The breakdown of BUPHENYL produces the byproduct phenylacetate (PAA), which may cause nervous system side effects.
Who should not take BUPHENYL?
Do not take BUPHENYL if you are allergic to phenylbutyrate. Call your doctor or go to the nearest hospital emergency room if you experience an allergic reaction while taking BUPHENYL.
What should I tell my doctor before taking BUPHENYL?
Before taking BUPHENYL, tell your doctor about any medical conditions, including if you:
What are possible side effects of BUPHENYL?
BUPHENYL may cause serious side effects, including:
See "What is the most important safety information I should know about BUPHENYL?"
The most common side effects of BUPHENYL include:
These are not all of the possible side effects of BUPHENYL. Call your doctor for medical advice about side effects.
For additional important safety information, click here for the Full Prescribing Information and Patient Package Insert and discuss with your doctor.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.